We Knew This Was Coming: "September Bivalent Jabs Much More Harmful" - Study

And we knew why. We hoped they wouldn't. It seems they did.

TrialSite News reports today: “Bivalent mRNA Vaccines High Rate of Adverse Events: Observational Study at University Hospital Wuerzburg in Germany”:

By September 2022, both Pfizer-BioNTech and Moderna made their bivalent COVID-19 vaccines by combining wild-type spike mRNA with Omicron variant of concern BA.1 or BA.4-5 spike available in Europe, the United Kingdom, and America with accelerated authorization by regulatory agencies.

…the rate of adverse reactions for the second booster was markedly higher among participants receiving the bivalent booster dose at 84.6% (95% CI 70.3-92.8%; 33/39) compared to the monovalent 51.4% (95% CI 35.9-66.6%; 19/37) vaccine (p=0.0028). The study team found that the rate of inability to work as well as prescribed medication need increased among the participants that received the bivalent BA.4-BA.5 booster dose.

….the Germany-based team declared that their results plus other studies point to the need for serious study on the “safety and reactogenicity of bivalent COVID-19 booster vaccines ultimately, to “aid clinical decision making in the choice between bivalent and monovalent vaccinations.”

And here is the link to the quoted study: “Bivalent BNT162b2mRNA original/Omicron BA.4-5 booster vaccination: adverse reactions and inability to work compared to the monovalent COVID-19 booster” (Medrxiv preprint, University Hospital Wuerzburg, Wuerzburg, Germany, 2022.11.08)

Let me disappoint the esteemed research team from the University Hospital Wuerzburg. It is NOT monovalent or bivalent that makes the difference to the worse. Here are some excerpts from a post I wrote back in July, “mRNA Jabs: You Haven't Seen Nothing Yet!”:

The mRNA in COMIRNATY [The new-and-improved mRNA that may be in the new bivalent jabs] is a single-stranded, 5’-capped mRNA encoding the full-length SARS-CoV-2 spike glycoprotein derived from the Wuhan-Hu-1 isolate (GenBank MN908947.3 and GenBank QHD43416.1). The antigen-coding RNA sequence is codon-optimized and contains two proline mutations ( 87P), which ensures an antigenically optimal trimerized pre-fusion confirmation (S-2P).

…So, one can increase tenfold to immunogenicity of the trimetic S-2P S spike stabilized in a prefusion configuration through a careful choice of proline substitutions. If so updated jabs still contain the original amount of the mRNA material, one shot will be equivalent to 10 original shots.

…But things are getting very serious as we speak. We see that they are now poised to release the “optimized trimeric version” of the S spike into wide circulation.

Seems like my predictions panned out again.

I encourage you to re-read “mRNA Jabs: You Haven't Seen Nothing Yet!” in light of the aforementioned German findings.